Overeating Could Be Caused By A Missing Brain Cell

Obese and binge eaters might not be victims of their circumstances and environments but rather due to genetic deficiency.

Scientists have discovered a new type of brain cell missing in most obese patients. The cell is also present in mice. The absence of the cell makes mice eat much more than mice with the cell present in their system.

According to Neuroscience Department Director Professor Dr. Richard Huganir:

“When the type of brain cell we discovered fires and sends off signals, our laboratory mice stop eating soon after.

“The signals seem to tell the mice they’ve had enough.”

According to scientists, the OGT Enzyme is a biological catalyst that regulates several processes that involve insulin and sugar chemistry. By adding a molecule called N-acetylclucosamine added to the body’s protein. The protein behaviour is then altercated. Upon deletion of the enzyme in mice, the mice had no restrictions on eating.

According to Dr. Olof Lagerlf, OGT interfered with the animal’s ability to sense when they were full. That included humans.

Prof Huganir added: “That result suggests that, in these cells, OGT helps maintain synapses.

“The number of synapses on these cells was so low that they probably aren’t receiving enough input to fire.

“In turn, that suggests that these cells are responsible for sending the message to stop eating.”

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